Yonsei Institute for Advanced Study

This presentation will describe our recent advances that leverage EVs for early cancer detection. Specifically, we will discuss the single EV analysis (SEA) platform that characterizes individual EVs for multiple protein markers. This method helps us unveil EV heterogeneity, which maximizes biological information content (specificity and sensitivity) for tumor-derived vesicles. We will review the SEA’s development and pilot application to diagnose early cancers.

Navigating the publishing process can seem mysterious and daunting. In this seminar, I hope to offer insight into the way the editors at the journal Cell work together to evaluate manuscript submissions, our decision-making processes and how to connect with the editors about your exciting science.

We will discuss the stable and selective photogeneration of aminium and aminyl radicals from the same amine precursor via tunable charge carrier imbalance condition enabled by the photoinduced anion exchange that opens unconventional but highly effective pathway of removing electrons irreversibly from the NCs. The coupling between the radicals photogenerated by CsPbX3 NCs, for which II-VI semiconductor NCs are catalytically inactive, will also be discussed.

In this talk, first, I will go over some of my past research on “Trehalose Glycopolymers and Hydrogels for Enhancing Protein Stability”. Then I will focus on my career journey by sharing my experience throughout Yonsei University, University of California, Los Angeles (graduate school), California Institute of Technology (post-doctoral), and being part of the US Biotech industry, Moderna. The talk will be informal, engaging, and interactive by encouraging active participation and questions from the audience.

On Tuesday, Jun 21st, 2022, the 9th Special Seminar of IBS CNM & NanoBME will be held at the Auditorium at IBS Hall at 4:00 p.m.

The presentation will explain timeresolved and time-gated FRET and the specific benefits for spectral and temporal luminescence multiplexing with different materials and instruments. Then, recent applications concerning multiplexed FRET biosensing and bioimaging in solution, in-vitro, in-situ, and in-vivo with a special focus on optical barcoding and molecular logic gates will be discussed.

Quantum dot is a semiconductor nanoparticle having a size of 1 to 10 nm, and it is easy to control color by size or composition, and has the advantage of high luminous efficiency and narrow peak width. Color is very important factor to realize images in the display, so superior quality values of displays are not achievable without a higher color gamut. Quantum dot is very promising emission material to realize high color gamut. In this seminar, I would like to talk about the application of QD to display and how Samsung has developed advanced display with QD.

On Tuesday, May 10th, 2022, the 6th Special Seminar of IBS CNM & NanoBME will be held at the Auditorium at IBS Hall at 4:30 p.m.

My academic journey with Bio AFM started with dendron-coated AFM probes that enable truly one-to-one interaction leading to enhanced accuracy and reproducibility. Such approach enables direct quantification of DNA, mRNA, microRNA, and proteins of low abundance without amplification or labeling. Also, we are pleased to demonstrate that the force mapping visualizes various biomolecules on cell surface at the nanometric resolution. The highest sensitivity and spatial resolution pave a new avenue for the bioanalysis. In particular, application for liquid biopsy is quite attractive because direct and sensitive nature allows us to diagnose cancer at early stages with the minimal false signals.

On Tuesday, April 19th, 2022, the third Special Seminar of IBS CNM & NanoBME will be held at the Auditorium at IBS Hall at 3:30 pm.