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Research Highlights

• [Precision Nanomedicine]   Sep 7, 2022
  Magnetogenetics with Piezo1 Mechanosensitive Ion Channel for CRISPR Gene Editing
  Wookjin Shin†, Sumin Jeong†, Jung-uk Lee, Soo Yeun Jeong, Jeonghong Shin, Hyongbum Henry Kim*, Jinwoo Cheon*, and Jae-Hyun Lee *(† equally contributed)
  Nano Lett., 22 (18), 7415–7422

  Regulation of genetic activity in single cells and tissues is pivotal to determine key cellular func...

• [Evolutionary Nanomaterials]   Mar 17, 2022
  Binary-State Scanning Probe Microscopy for Parallel Imaging
  Gwangmook Kim, Eoh Jin Kim, Hyung Wan Do, Min-Kyun Cho, Sungsoon Kim, Shinill Kang, Dohun Kim, Jinwoo Cheon, and Wooyoung Shim*
  Nat. Commun., 13, 1438

  Scanning probe microscopy techniques, such as atomic force microscopy and scanning tunnelling micros...

• [Precision Nanomedicine]   Oct 20, 2021
  A Rapid Assay Provides On-Site Quantification of Tetrahydrocannabinol in Oral Fluid
  Hojeong Yu, Hoyeon Lee, Jiyong Cheong, Sang Won Woo, Juhyun Oh, Hyun-kyung Oh, Jae-Hyun Lee, Hui Zheng, Cesar M. Castro, Yeong-Eun Yoo, Min-Gon Kim, Jinwoo Cheon, Ralph Weissleder, and Hakho Lee*
  Sci. Transl. Med., 13 (616), 1-10

  Tetrahydrocannabinol (THC), the primary psychoactive ingredient of cannabis, impairs cognitive and m...

• [Evolutionary Nanomaterials]   Apr 15, 2021
  Magnetothermally Activated Nanometer-level Modular Functional Group Grafting of Nanoparticles
  Yongjun Lim, Seung-hyun Noh, Tae-Hyun Shin, Jung-uk Lee, Dominik Lungerich, Jae-Hyun Lee, and Jinwoo Cheon*
  Nano Lett., 21 (8), 3649–3656

  Nanoparticles with multifunctionality and high colloidal stability are essential for biomedical appl...

• [Precision Nanomedicine]   Mar 8, 2021
  High-Resolution T1 MRI via Renally Clearable Dextran Nanoparticles with an Iron Oxide Shell
  Tae-Hyun Shin†, Pan Ki Kim†, Sunghwi Kang, Jiyong Cheong, Soojin Kim, Yongjun Lim, Wookjin Shin, Joon-Yong Jung, Jungsu D. Lah, Byoung Wook Choi*, and Jinwoo Cheon* († equally contributed)
  Nat. Biomed. Eng., 5 (3), 252-263

  Contrast agents for magnetic resonance imaging (MRI) improve anatomical visualizations. However, owi...

• [Precision Nanomedicine]   Jan 28, 2021
  Non-Contact Long-Range Magnetic Stimulation of Mechanosensitive Ion Channels in Freely Moving Animals
  Jung-uk Lee, Wookjin Shin, Yongjun Lim, Jungsil Kim, Woon Ryoung Kim, Heehun Kim, Jae-Hyun Lee, and Jinwoo Cheon*
  Nat. Mater., 20 (7), 1029–1036

  Among physical stimulation modalities, magnetism has clear advantages, such as deep penetration and ...

• [Precision Nanomedicine]   Dec 3, 2020
  Fast Detection of SARS-CoV-2 RNA via the Integration of Plasmonic Thermocycling and Fluorescence Detection in a Portable Device
  Jiyong Cheong†, Hojeong Yu†, Chang Yeol Lee, Jung-uk Lee, Hyun-jung Choi, Jae-Hyun Lee*, Hakho Lee*, and Jinwoo Cheon* († equally contributed)
  Nat. Biomed. Eng., 4, 1159–1167

  The diagnosis of severe acute respiratory syndrome 2 (SARS-CoV-2) infection by quantitative PCR with...

• [Nanobio Interface]   Oct 22, 2019
  Mechanoluminescent, Air-Dielectric MoS2 Transistors as Active-Matrix Pressure Sensors for Wide Detection Ranges from Footsteps to Cellular Motions
  Jiuk Jang†, Hyobeom Kim†, Sangyoon Ji, Ha Jun Kim, Min Soo Kang, Tae Soo Kim, Jong-eun Won, Jae-Hyun Lee, Jinwoo Cheon*, Kibum Kang*, Won Bin Im*, and Jang-Ung Park* († equally contributed)
  Nano Lett., 20 (1), 66-74

  Tactile pressure sensors as flexible bioelectronic devices have been regarded as the key component f...

• [Precision Nanomedicine]   Aug 28, 2019
  Magnetic Control of Axon Navigation in Reprogrammed Neurons
  Yoonhee Jin†, Jung-uk Lee†, Eunna Chung, Kisuk Yang, Jin Kim, Ji-wook Kim, Jong Seung Lee, Ann-Na Cho, Taekyu Oh, Jae-Hyun Lee, Seung-Woo Cho*, and Jinwoo Cheon* († equally contributed)
  Nano Lett., 19 (9), 6517-6523

  While neural cell transplantation represents a promising therapy for neurodegenerative diseases, the...

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