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Jae-Hyun Lee†, Kuan-Ju Chen†, Seung-Hyun Noh, Mitch Andre Garcia, Hao Wang, Wei-Yu Lin, Heeyeong Jeong, Brian Junoh Kong, David B. Stout, Jinwoo Cheon*, and Hsian-Rong Tseng* († equally contributed)
On-Demand Drug Release System for In Vivo Cancer Treatmentthrough Self-Assembled Magnetic Nanoparticles
Angew. Chem. Int. Ed., 52 (16), 4384-4388
On-Demand Drug Release System for In Vivo Cancer Treatmentthrough Self-Assembled Magnetic Nanoparticles
Angew. Chem. Int. Ed., 52 (16), 4384-4388
Date: Mar 20, 2013
On‐demand drug release: Magnetothermally responsive drug‐encapsulated supramolecular nanoparticles for on‐demand drug release in vivo have been developed. The remote application of an alternative magnetic field heats the magnetic particles that effectively trigger the release of the drug. An acute drug concentration can be delivered to the tumor in vivo, resulting in an improved therapeutic outcome.
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