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Yeong Shin Yim, Jin-sil Choi, Gun Tae Kim, Chul Hoon Kim, Tae-Hyun Shin, Dong Goo Kim*, and Jinwoo Cheon*
A Facile Approach for the Delivery of Inorganic Nanoparticles into the Brain by Passing Through the Blood–Brain Barrier (BBB)
Chem. Commun., 48, 61-63
A Facile Approach for the Delivery of Inorganic Nanoparticles into the Brain by Passing Through the Blood–Brain Barrier (BBB)
Chem. Commun., 48, 61-63
Date: Nov 7, 2011
This study provides an easy and simple method to obtain inorganic nanoparticles that can penetrate the blood–brain barrier, the heavily guarded system in the brain, via cross-linked serum albumin surface coatings. Their intact BBB permeability was confirmed in both in vitro and in vivo tests.
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