|[Nanobio Interface] Mihály Vöröslakos, Kanghwan Kim, Nathan Slager, Eunah Ko, Sungjin Oh,Saman S. Parizi, Blake Hendrix, John P. Seymour, Kensall D. Wise, György Buzsáki*, Antonio Fernández-Ruiz*, and Euisik Yoon*
HectoSTAR𝝁LED Optoelectrodes for Large-Scale,High-Precision In Vivo Opto-Electrophysiology
Adv. Sci., 9 (18), 2105414 (Apr 22, 2022) DOI : https://doi.org/10.1002/advs.202105414
Dynamic interactions within and across brain areas underlie behavioral and cognitive functions. To u...
|[Precision Nanomedicine] Younggwang Kim, Seungho Lee, Soohyuk Cho, Jinman Park, Dongwoo Chae, Taeyoung Park, John D. Minna, and Hyongbum Henry Kim*
High-Throughput Functional Evaluation of Human Cancer-Associated Mutations Using Base Editors
Nat. Biotechnol., 40, 874–884 (Apr 11, 2022) DOI : https://doi.org/10.1038/s41587-022-01276-4
Comprehensive phenotypic characterization of the many mutations found in cancer tissues is one of th...
|[Precision Nanomedicine] Dheeraj S. Roy*, Young-Gyun Park, Minyoung E. Kim, Ying Zhang, Sachie K. Ogawa, Nicholas DiNapoli, Xinyi Gu, Jae H. Cho, Heejin Choi, Lee Kamentsky, Jared Martin, Olivia Mosto, Tomomi Aida, Kwanghun Chung*, and Susumu Tonegawa*
Brain-Wide Mapping Reveals that Engrams for a Single Memory are Distributed Across Multiple Brain Regions
Nat. Commun., 13 (1), 1799 (Apr 4, 2022) DOI : https://doi.org/10.1038/s41467-022-29384-4
Neuronal ensembles that hold specific memory (memory engrams) have been identified in the hippocampu...
|[Evolutionary Nanomaterials & Nanodevices] Dongxin Liu, Satori Kowashi, Takayuki Nakamuro*, Dominik Lungerich, Kaoru Yamanouchi, Koji Harano*, and Eiichi Nakamura*
Ionization and Electron Excitation of C60 in a Carbon Nanotube: A Variable Temperature/Voltage Transmission Electron Microscopic Study
PNAS, 119 (15), e2200290119 (Apr 4, 2022) DOI : https://doi.org/10.1073/pnas.2200290119
There is increasing attention to chemical applications of transmission electron microscopy, which is...
|[Precision Nanomedicine] Suran Kim†, Sungjin Min†, Yi Sun Choi, Sung-Hyun Jo, Jae Hun Jung, Kyusun Han, Jin Kim, Soohwan An, Yong Woo Ji, Yun-Gon Kim, and Seung-Woo Cho* († equally contributed)
Tissue Extracellular Matrix Hydrogels as Alternatives to Matrigel for Culturing Gastrointestinal Organoids
Nat. Commun., 13, 1692 (Mar 30, 2022) DOI : https://doi.org/10.1038/s41467-022-29279-4
Matrigel, a mouse tumor extracellular matrix protein mixture, is an indispensable component of most ...
|[Evolutionary Nanomaterials & Nanodevices] Hyeonwoo Lee, Mikko Partanen, Mingyu Lee, Sunghoon Jeong, Hyeung Joo Lee, Kwanpyo Kim, Wonhyoung Ryu*, Kishan Dholakia*, and Kyunghwan Oh*
A Laser-Driven Optical Atomizer: Photothermal Generation and Transport of Zeptoliter-Droplets along a Carbon Nanotube Deposited Hollow Optical Fiber
Nanoscale, 14 (13), 5138-5146 (Mar 18, 2022) DOI : https://doi.org/10.1039/D1NR06211E
From mechanical syringes to electric field-assisted injection devices, precise control of liquid dro...
|[Evolutionary Nanomaterials & Nanodevices] Gwangmook Kim, Eoh Jin Kim, Hyung Wan Do, Min-Kyun Cho, Sungsoon Kim, Shinill Kang, Dohun Kim, Jinwoo Cheon, and Wooyoung Shim*
Binary-State Scanning Probe Microscopy for Parallel Imaging
Nat. Commun., 13, 1438 (Mar 17, 2022) DOI : https://doi.org/10.1038/s41467-022-29181-z
Scanning probe microscopy techniques, such as atomic force microscopy and scanning tunnelling micros...
|[Precision Nanomedicine] Byunghwa Noh†, John Hoon Rim†, Ramu Gopalappa†, Haiyue Lin, Kyu Min Kim, Min Jin Kang, Heon Yung Gee*, Jae Young Choi*, Hyongbum Henry Kim*, and Jinsei Jung* († equally contributed)
In Vivo Outer Hair Cell Gene Editing Ameliorates Progressive Hearing Loss in Dominant-Negative Kcnq4 Murine Model
Theranostics, 12 (5), 2465-2482 (Feb 28, 2022) DOI : https://doi.org/10.7150/thno.67781
Outer hair cell (OHC) degeneration is a major cause of progressive hearing loss and presbycusis. Des...
|[Nanobio Interface] Manuel Valero*, Ipshita Zutshi , Euisik Yoon, and György Buzsáki*
Probing Subthreshold Dynamics of Hippocampal Neurons by Pulsed Optogenetics
Science, 375 (6580), 570-574 (Feb 3, 2022) DOI : https://doi.org/10.1126/science.abm1891
Understanding how excitatory (E) and inhibitory (I) inputs are integrated by neurons requires monito...
|[Precision Nanomedicine] Jung Min Lim, and Hyongbum Henry Kim*
Basic Principles and Clinical Applications of CRISPR-Based Genome Editing
Yonsei Med. J., 63 (2), 105-113 (Jan 20, 2022) DOI : https://doi.org/10.3349/ymj.2022.63.2.105
Advances in sequencing technologies have facilitated the discovery of previously unknown genetic var...