Yonsei Advanced Science Institute

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[Precision Nanomedicine] Hojeong Yu, Hoyeon Lee, Jiyong Cheong, Sang Won Woo, Juhyun Oh, Hyun-Kyung Oh, Jae-Hyun Lee, Hui Zheng, Cesar M. Castro, Yeong-Eun Yoo, Min-Gon Kim, Jinwoo Cheon, Ralph Weissleder, and Hakho Lee*
A Rapid Assay Provides On-Site Quantification of Tetrahydrocannabinol in Oral Fluid
Sci. Transl. Med, 13 (616), 1-10
 (Oct 20, 2021)
  DOI : https://doi.org/10.1126/scitranslmed.abe2352

Abstract Tetrahydrocannabinol (THC), the primary psychoactive ingredient of cannabis, impairs cogni...

[Yonhap News], [Hankook Ilbo], [NEWSIS]

[Precision Nanomedicine] Young Hun Kim†, Man Sup Kwak†, Bin Lee, Jae Min Shin, Sowon Aum, In Ho Park, Min Goo Lee, and Jeon-Soo Shin († equally contributed)
Secretory Autophagy Machinery and Vesicular Trafficking Are Involved in HMGB1 Secretion
Autophagy, 17 (9), 2345-2362
 (Oct 5, 2021)
  DOI : http://doi.org/10.1080/15548627.2020.1826690

Nuclear protein HMGB1 is secreted in response to various stimuli and functions as a danger-associate...

[Precision Nanomedicine] Myungjae Song†, Jung Min Lim†, Seonwoo Min, Jeong-Seok Oh, Dong Young Kim, Jae-Sung Woo, Hiroshi Nishimasu, Sung-Rae Cho, Sungroh Yoon, and Hyongbum Henry Kim* († equally contributed)
Generation of a More Efficient Prime Editor 2 by Addition of the Rad51 DNA-Binding Domain
Nat. Commun., 12 (1), 1-8
 (Sep 23, 2021)
  DOI : http://doi.org/10.1038/s41467-021-25928-2

Although prime editing is a promising genome editing method, the efficiency of prime editor 2 (PE2) ...

[Precision Nanomedicine] Su Kyeom Kim, Yu Heun Kim, Sewon Park, and Seung-Woo Cho*
Organoid Engineering with Microfluidics and Biomaterials for Liver, Lung Disease, and Cancer Modeling
Acta Biomater., 132, 37-51
 (Sep 15, 2021)
  DOI : http://doi.org/10.1016/j.actbio.2021.03.002

As life expectancy improves and the number of people suffering from various diseases increases, the ...

[Precision Nanomedicine] Jisoo Shin, Eun Hye Kang, Soojeong Choi, Eun Je Jeon, Jung Ho Cho, Donyoung Kang, Hyungsuk Lee, In Sik Yun*, and Seung-Woo Cho*
Tissue-Adhesive Chondroitin Sulfate Hydrogel for Cartilage Reconstruction
ACS Biomater. Sci. Eng., 7 (9), 4230-4243
 (Sep 13, 2021)
  DOI : http://doi.org/10.1021/acsbiomaterials.0c01414

Chondroitin sulfate (CS), the main component of cartilage extracellular matrix, has attracted attent...

[Precision Nanomedicine] Hyewon Jang†, Dong Hyun Jo†, Chang Sik Cho, Jeong Hong Shin, Jung Hwa Seo, Goosang Yu, Ramu Gopalappa, Daesik Kim, Sung-Rae Cho, Jeong Hun Kim*, and Hyongbum Henry Kim* († equally contributed)
Application of Prime Editing to the Correction of Mutations and Phenotypes in Adult Mice with Liver and Eye Diseases
Nat. Biomed. Eng, 6 (2), 181-194
 (Aug 24, 2021)
  DOI : https://doi.org/10.1038/s41551-021-00788-9

The use of prime editing—a gene-editing technique that induces small genetic changes without t...

[Precision Nanomedicine] Jin Kim†, Kyung-Tae Lee†, Jong Seung Lee, Jisoo Shin, Baofang Cui, Kisuk Yang, Yi Sun Choi, Nakwon Choi, Soo Hyun Lee, Jae-Hyun Lee, Yong-Sun Bahn*, and Seung-Woo Cho* († equally contributed)
Fungal Brain Infection Modelled in a Human-Neurovascular-Unit-on-a-Chip with a Functional Blood–Brain Barrier
Nat. Biomed. Eng., 5 (8), 830-846
 (Aug 1, 2021)
  DOI : http://doi.org/10.1038/s41551-021-00743-8

The neurovascular unit, which consists of vascular cells surrounded by astrocytic end-feet and n...

[Nanobio Interface] Jiuk Jang†, Young-Geun Park†, Eunkyung Cha, Sangyoon Ji, Hyunbin Hwang, Gon Guk Kim, Jungho Jin*, and Jang-Ung Park* († equally contributed)
3D Heterogeneous Device Arrays for Multiplexed Sensing Platforms Using Transfer of Perovskites
Adv. Mater., 33 (30), 2101093
 (Jul 28, 2021)
  DOI : https://doi.org/10.1002/adma.202101093 SECTIONS

Despite recent substantial advances in perovskite materials, their 3D integration capability for nex...

[Evolutionary Nanomaterials & Nanodevices] Jong-Young Lee†, Jong Hun Kim†, Yeonjoon Jung, June Chul Shin, Yangjin Lee, Namwon Kim, Arend M. van der Zande, Jangyup Son*, and Gwan-Hyoung Lee* († equally contributed)
Evolution of Defect Formation During Atomically Precise Desulfurization of Monolayer MoS2
Commun. Mater, 2, 80
 (Jul 23, 2021)
  DOI : https://doi.org/10.1038/s43246-021-00185-4

Structural symmetry-breaking is a key strategy to modify the physical and chemical properties of two...

[Evolutionary Nanomaterials & Nanodevices] Connor Orrison, Jeremy R. Meeder, Bowen Zhang, Joseph Puthenpurayil, Michael B. Hall, Michael Nippe*, and Dong Hee Son*
Efficient Redox-Neutral Photocatalytic Formate to Carbon Monoxide Conversion Enabled by Long-Range Hot Electron Transfer from Mn-Doped Quantum Dots
J. Am. Chem. Soc., 143 (27), 10292-10300
 (Jul 14, 2021)
  DOI : https://doi.org/10.1021/jacs.1c03844

Energetic hot electrons generated in Mn-doped quantum dots (QDs) via exciton-to-hot-electron upconve...


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