연세대학교 고등과학원 (IBS CNM & NanoBME)

Research

Publications

	[Evolutionary Nanomaterials & Nanodevices] Mikhail Feofanov , Dominik Lungerich, Vladimir Akhmetov, and Konstantin Amsharov* Synthesis of Dumbbell-Like DBATT Dimers** ChemistrySelect, 6 (39), 10671-10673 (Oct 20, 2021) DOI : http://doi.org/10.1002/slct.202103363 Herein we report a novel approach to a very interesting class of compounds containing two acene-base...
	[Precision Nanomedicine] Hojeong Yu, Hoyeon Lee, Jiyong Cheong, Sang Won Woo, Juhyun Oh, Hyun-Kyung Oh, Jae-Hyun Lee, Hui Zheng, Cesar M. Castro, Yeong-Eun Yoo, Min-Gon Kim, Jinwoo Cheon, Ralph Weissleder, and Hakho Lee* A Rapid Assay Provides On-Site Quantification of Tetrahydrocannabinol in Oral Fluid Sci. Transl. Med, 13 (616), 1-10 (Oct 20, 2021) DOI : https://doi.org/10.1126/scitranslmed.abe2352 Abstract Tetrahydrocannabinol (THC), the primary psychoactive ingredient of cannabis, impairs cogni... [Yonhap News], [Hankook Ilbo], [NEWSIS]
	[Precision Nanomedicine] Young Hun Kim†, Man Sup Kwak†, Bin Lee, Jae Min Shin, Sowon Aum, In Ho Park, Min Goo Lee, and Jeon-Soo Shin († equally contributed) Secretory Autophagy Machinery and Vesicular Trafficking Are Involved in HMGB1 Secretion Autophagy, 17 (9), 2345-2362 (Oct 5, 2021) DOI : http://doi.org/10.1080/15548627.2020.1826690 Nuclear protein HMGB1 is secreted in response to various stimuli and functions as a danger-associate...
	[Precision Nanomedicine] Myungjae Song†, Jung Min Lim†, Seonwoo Min, Jeong-Seok Oh, Dong Young Kim, Jae-Sung Woo, Hiroshi Nishimasu, Sung-Rae Cho, Sungroh Yoon, and Hyongbum Henry Kim* († equally contributed) Generation of a More Efficient Prime Editor 2 by Addition of the Rad51 DNA-Binding Domain Nat. Commun., 12 (1), 1-8 (Sep 23, 2021) DOI : http://doi.org/10.1038/s41467-021-25928-2 Although prime editing is a promising genome editing method, the efficiency of prime editor 2 (PE2) ...
	[Precision Nanomedicine] Su Kyeom Kim, Yu Heun Kim, Sewon Park, and Seung-Woo Cho* Organoid Engineering with Microfluidics and Biomaterials for Liver, Lung Disease, and Cancer Modeling Acta Biomater., 132, 37-51 (Sep 15, 2021) DOI : http://doi.org/10.1016/j.actbio.2021.03.002 As life expectancy improves and the number of people suffering from various diseases increases, the ...
	[Precision Nanomedicine] Jisoo Shin, Eun Hye Kang, Soojeong Choi, Eun Je Jeon, Jung Ho Cho, Donyoung Kang, Hyungsuk Lee, In Sik Yun, and Seung-Woo Cho Tissue-Adhesive Chondroitin Sulfate Hydrogel for Cartilage Reconstruction ACS Biomater. Sci. Eng., 7 (9), 4230-4243 (Sep 13, 2021) DOI : http://doi.org/10.1021/acsbiomaterials.0c01414 Chondroitin sulfate (CS), the main component of cartilage extracellular matrix, has attracted attent...
	[Precision Nanomedicine] Hyewon Jang†, Dong Hyun Jo†, Chang Sik Cho, Jeong Hong Shin, Jung Hwa Seo, Goosang Yu, Ramu Gopalappa, Daesik Kim, Sung-Rae Cho, Jeong Hun Kim, and Hyongbum Henry Kim († equally contributed) Application of Prime Editing to the Correction of Mutations and Phenotypes in Adult Mice with Liver and Eye Diseases Nat. Biomed. Eng, 6 (2), 181-194 (Aug 24, 2021) DOI : https://doi.org/10.1038/s41551-021-00788-9 The use of prime editing—a gene-editing technique that induces small genetic changes without t...
	[Precision Nanomedicine] Jin Kim†, Kyung-Tae Lee†, Jong Seung Lee, Jisoo Shin, Baofang Cui, Kisuk Yang, Yi Sun Choi, Nakwon Choi, Soo Hyun Lee, Jae-Hyun Lee, Yong-Sun Bahn, and Seung-Woo Cho († equally contributed) Fungal Brain Infection Modelled in a Human-Neurovascular-Unit-on-a-Chip with a Functional Blood–Brain Barrier Nat. Biomed. Eng., 5 (8), 830-846 (Aug 1, 2021) DOI : http://doi.org/10.1038/s41551-021-00743-8 The neurovascular unit, which consists of vascular cells surrounded by astrocytic end-feet and n...
	[Nanobio Interface] Jiuk Jang†, Young-Geun Park†, Eunkyung Cha, Sangyoon Ji, Hyunbin Hwang, Gon Guk Kim, Jungho Jin, and Jang-Ung Park († equally contributed) 3D Heterogeneous Device Arrays for Multiplexed Sensing Platforms Using Transfer of Perovskites Adv. Mater., 33 (30), 2101093 (Jul 28, 2021) DOI : https://doi.org/10.1002/adma.202101093 SECTIONS Despite recent substantial advances in perovskite materials, their 3D integration capability for nex...
	[Evolutionary Nanomaterials & Nanodevices] Jong-Young Lee†, Jong Hun Kim†, Yeonjoon Jung, June Chul Shin, Yangjin Lee, Namwon Kim, Arend M. van der Zande, Jangyup Son, and Gwan-Hyoung Lee († equally contributed) Evolution of Defect Formation During Atomically Precise Desulfurization of Monolayer MoS2 Commun. Mater, 2, 80 (Jul 23, 2021) DOI : https://doi.org/10.1038/s43246-021-00185-4 Structural symmetry-breaking is a key strategy to modify the physical and chemical properties of two...