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[Precision Nanomedicine] Hui Kwon Kim†, Seonwoo Min†, Myungjae Song, Soobin Jung, Jae Woo Choi, Younggwang Kim, Sangeun Lee, Sungroh Yoon*, and Hyongbum (Henry) Kim* († equally contributed)
Deep Learning Improves Prediction of CRISPR–Cpf1 Guide RNA Activity
Nat. Biotechnol., 36 (3), 239-241
 (Jan 29, 2018)
  DOI : https://doi.org/10.1038/nbt.4061

We present two algorithms to predict the activity of AsCpf1 guide RNAs. Indel frequencies for 15,000...

[Precision Nanomedicine] Wonjoo Kim, Sangeun Lee, Han Sang Kim, Minjung Song, Yong Hoon Cha, Young-Hoon Kim, Jeonghong Shin, Eun-Seo Lee, Yeonsoo Joo, Jae J. Song, Eun Ju Choi, Jae W. Choi, Jinu Lee, Moonkyung Kang, Jong In Yook, Min Goo Lee, Yeon-Soo Kim, Soonmyung Paik, and Hyongbum (Henry) Kim*
Targeting Mutant KRAS with CRISPR-Cas9 Controls Tumor Growth
Genome Res., 28, 374-382
 (Jan 11, 2018)
  DOI : https://doi.org/10.1101/gr.223891.117

KRAS is the most frequently mutated oncogene in human tumors, and its activating mutations represent...

[Precision Nanomedicine] Jung Ho Cho†, Jung Seung Lee†, Jisoo Shin, Eun Je Jeon, Soohwan An, Yi Sun Choi, and Seung‐Woo Cho* († equally contributed)
Ascidian‐Inspired Fast‐Forming Hydrogel System for Versatile Biomedical Applications: Pyrogallol Chemistry for Dual Modes of Crosslinking Mechanism
Adv. Funct. Mater., 28 (6), 1705244
 (Dec 15, 2017)
  DOI : https://doi.org/10.1002/adfm.201705244

ascidians, drug delivery, fast gelation, hydrogels, pyrogallol, tissue engineering

[Precision Nanomedicine] Kisoo Park, Hoyoung Kim, Soojin Kim, Kyungheon Lee, Sohyeon Park, Jun Song, Changwook Min, Farhana Khanam, Rasheduzzaman Rashu, Taufiqur Rahman Bhuiyan, Edward T. Ryan, Firdausi Qadri, Ralph Weissleder, Jinwoo Cheon*, Richelle C. Charles*, and Hakho Lee*
Nanomagnetic System for Rapid Diagnosis of Acute Infection
ACS Nano, 11 (11), 11425-11432
 (Nov 9, 2017)
  DOI : https://doi.org/10.1021/acsnano.7b06074

Biosensors, magnetic nanoparticles, nuclear magnetic resonance, enteric fever, host response, acute infections

[Evolutionary Nanomaterials & Nanodevices] Ho Jin, Bongkwan Baek, Doyun Kim, Fanglue Wu, James D. Batteas, Jinwoo Cheon, and Dong Hee Son​*
Effects of Direct Solvent-Quantum Dot Interaction on the Optical Properties of Colloidal Monolayer WS2 Quantum Dots
Nano Lett., 17 (12), 7471-7477
 (Oct 27, 2017)
  DOI : https://doi.org/10.1021/acs.nanolett.7b03381

Colloidal quantum dots, monolayer WS2, transition metal dichalcogenide, photoluminescence

[Evolutionary Nanomaterials & Nanodevices] Changwook Min, Jongmin Park, Jae Kyoung Mun, Yongjun Lim, Jouha Min, Jong-Won Lim, Dong-Min Kang, Ho-Kyun Ahn, Tae-Hyun Shin, Jinwoo Cheon, Hae-Seung Lee, Ralph Weissleder, Cesar M. Castro*, and Hakho Lee*
Integrated MicroHall Magnetometer to Measure the Magnetic Properties of Nanoparticles
Lab Chip, 17 (23), 4000-4007
 (Aug 31, 2017)
  DOI : https://doi.org/10.1039/C7LC00934H

Magnetic nanoparticles, characterization chip, integrated microHall magnetometer

[Nanobio Interface] Ji-wook Kim†, Daeha Seo†, Jung-uk Lee†, Kaden M. Southard, Yongjun Lim, Daehyun Kim, Zev J. Gartner, Young-wook Jun†*, and Jinwoo Cheon* († equally contributed)
Single-Cell Mechanogenetics Using Monovalent Magnetoplasmonic Nanoparticles
Nat. Protoc., 12, 1871-1889
 (Aug 17, 2017)
  DOI : https://doi.org/10.1038/nprot.2017.071

Selected as Nature Protocols website main banner paper​

[Nanobio Interface] Tae-Hyun Shin and Jinwoo Cheon*
Synergism of Nanomaterials with Physical Stimuli for Biology and Medicine
Acc. Chem. Res., 50 (3), 567-572
 (Mar 21, 2017)
  DOI : https://doi.org/10.1021/acs.accounts.6b00559

Published as part of the Accounts of Chemical Research ​special issue​ "Holly Grails in Chemistry"

[Evolutionary Nanomaterials & Nanodevices] Seung-hyun Noh†, Seung Ho Moon†, Tae-Hyun Shin, Yongjun Lim, and Jinwoo Cheon* († equally contributed)
Recent Advances of Magneto-Thermal Capabilities of Nanoparticles: From Design Principles to Biomedical Applications
Nano Today, 13, 61-76
 (Mar 16, 2017)
  DOI : https://doi.org/10.1016/j.nantod.2017.02.006

Emerging approaches for the use of heat-generating nanoparticles for dual-mode magnetic hyperthermia, magnetothermally triggered drug delivery, and the magnetothermal control of cellular activities.

[Precision Nanomedicine] Jin-sil Choi†, Soojin Kim†, Dongwon Yoo, Tae-Hyun Shin, Hoyoung Kim, Muller D. Gomes, Sun Hee Kim, Alexander Pines, and Jinwoo Cheon* († equally contributed)
Distance-Dependent Magnetic Resonance Tuning as a Versatile MRI Sensing Platform for Biological Targets
Nat. Mater., 16 (5), 537-542
 (Feb 6, 2017)
  DOI : https://doi.org/10.1038/nmat4846

Nanoscale distance-dependent phenomena, such as Forster resonance energy transfer, are important int...

[KBS], [ChosunBiz], [SBS], [JTBC], [YNA]

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